Targeting pre-miRNA by Peptide Nucleic Acids
نویسندگان
چکیده
منابع مشابه
Targeting pre-miRNA by Peptide Nucleic Acids
PNAs conjugated to carrier peptides have been employed for the targeting of miRNA precursor, with the aim to develop molecules able to interfere in the pre-miRNA processing. The capability of the molecules to bind pre-miRNA has been tested in vitro by fluorescence assayes on Thiazole Orange labeled molecules and in vivo, in K562 cells, evaluating the amount of miRNA produced after treatment of ...
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ژورنال
عنوان ژورنال: Artificial DNA: PNA & XNA
سال: 2012
ISSN: 1949-095X,1949-0968
DOI: 10.4161/adna.20911